Sarcouncil Journal of Medical Sciences

Abstract: Background: Autoimmune diseases are well established to afflict many organ systems and can lead to severe gynecological issues. However, their overall impact on both systemic internal medicine and gynecology is not thoroughly explored. Aim: The aim of this study was to analyze the impact of autoimmune diseases on gynecological health and their association with systemic symptoms during a 12-month follow-up in 110 patients. Methodology: The research included a sample of 110 female patients suffering from multiple autoimmune disorders from Baghdad, Iraq hospitals during the January 2024 – January 2025 follow–up period. Baseline demographic data, gynecologic health parameters, and systemic signs were collected and followed longitudinally for a period of 12 months. Patient-assessed quality of life was measured using standardized patient questionnaires. Gynecologic symptom change, systemic health, and patient satisfaction regarding treatment regimens were calculated based on the data obtained. Summary Results At baseline, 60% of the patients had a history of dysmenorrhea, and systemic symptoms such as fatigue and arthralgia were prevalent in 75% and 68% of patients, respectively. On follow-up during the 12-month duration, there was a tremendous reduction in the prevalence of gynecological and systemic symptoms, with 70% of the study participants having an improvement in gynecological well-being and 60% with reduced systemic symptoms. Quality of life assessment showed substantial physical functioning (from 60 ± 10 to 75 ± 8) and mental health (from 65 ± 9 to 80 ± 7) improvement. High patient satisfaction with treatment regimens was reported, with 75% being satisfied. Conclusion: The findings indicate that autoimmune illness exerts a major impact on gynecologic health and internal systemic medicine. However, it is possible to achieve dramatic symptom and quality-of-life improvement with optimal management, where multidisciplinary care strategies and routine surveillance will enhance patient outcomes maximally for this population.